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Centre for Membrane Pumps in Cells and Disease - PUMPkin


The Centre for Membrane Pumps in Cells and Disease - PUMPkin is a Centre of Excellence funded by the Danish National Research Foundation.

PUMPkin research investigates the structure and mechanism of membrane proteins of the P-type family, such as the sodium pump, proton pump, calcium pump, heavy metal pumps and lipid flippases, as well as (patho)physiological aspects of their function, and their potential as drug targets in human disease and pathogens.


2015.02.05 | Research news

Ion pumps in cells and their importance for nervous disorders

More knowledge about cellular ion pumps will pave the way for improved treatment of neurological disorders. Molecular Biologist Hanne Poulsen has just been awarded a Lundbeck Foundation Fellowship valued at DKK 10 million for a five-year research project.

2015.01.28 | Research news

New steroid-bound structures of the sodium-potassium pump broaden our knowledge about this enzyme

Na+,K+-ATPase is the ion pump responsible for maintenance of the electrochemical gradients of Na+ and K+ across the membrane of animal cells. Cardiotonic steroids constitute a broad class of specific Na+,K+-ATPase inhibitors, including drugs of clinical importance with multiple physiological effects. The existence of several endogenous cardiotonic…

2014.10.30 | Research news

New knowledge about neurotransmitter pathways in the brain

Insight into transport mechanisms in brain cells is extremely important in connection with disorders such as schizophrenia, epilepsy and depression, as well as in connection with producing the right medicine. Defects in proteins responsible for the transport of neurotransmitters are actually related to psychological and neurological disorders, and…

2014.08.18 | Research news

Don’t zinc - do!

Aarhus University’s PUMPkin Centre – a Centre of Excellence funded by the Danish National Research Foundation – has just succeeded in ‘taking’ the first photos of the mechanism that transports zinc out of the cells of organisms such as bacteria and plants. The study has just been published in Nature.

2014.01.20 | Awards

Master student Rasmus Pihl receives Novo Nordisk Scholarship

Rasmus Pihl er blevet tildelt et Novo Nordisk Scholarship, der giver ham økonomisk støtte under hans specialeprojekt, som udføres under vejledning af professor Poul Nissen og forskningsstipendiat Hanne Poulsen ved Institut for Molekylærbiologi og Genetik. Stipendiet giver udvalgte, dygtige studerende tid til at hellige sig deres speciale på fuld…

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Highlights 2011 from the PUMPkin Centre

Read about the scientific highlights during 2011, including a few words on our midterm evaluation.

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Revised 2015.02.12

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