Prestigeous funding to Karin Lykke-Hartmann

Prestigeous funding to Karin Lykke-Hartmann

The Parkinson Foundation has awarded Asso. Professor Karin Lykke-Hartmann with a prestigeous funding for her research project:

"Dissecting dopaminergic signaling in basal ganglie"

Rapid onset dystonia-parkinsonism (RDP) is a disease that begins early in life and which is know to cause mutations in the gene ATP1A3. Karin Lykke-Hartmann and her research group have mapped this protein in brains from adult mice and found that it primarily occurs in a certain part of the dopaminergic cells in the brain.

The protein is important for maintenance of the electrolytes exchange in the neurons.

The research group have used a mouse model ("knock out mouse"), which can give information on who ATP1A3 affects the signal routes in the basal ganglia. RDP is not the same as PArkinson disease, but since the protein is found in the same cells, which suffer when Parkinson is present, these studies can contribute to the understanding of signal routes in Parkinson disease.

Read more at the website of the Parkinson Foundation

Announced: 11. October 2011