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The CPA toxin (purple) sits right at the edge of the membrane and prevents the calcium ions (the light blue balls) from being transported to the other side of the membrane. Under the stop sign you see the toxin CPA (purple) which acts as a plug in the calcium pump.

2009.09.23 | Research news

Researchers identify mechanism of a known toxic compound in food

The toxic compound cyclopiazonic acid (CPA) has been known for many years, but it is only now that researchers have found out how the toxic compound works. This discovery will help researchers to develop new antibiotics.

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Comments on content: 
Karen Bech-Pedersen

Revised 04.07.2017

The Centre for Membrane Pumps in Cells and Disease

Aarhus University
The Department of Molecular Biology and Genetics

The Department of Molecular Biology and Genetics is located at six different addresses:

  • The Science Park - Gustav Wieds Vej 10, 8000 Aarhus C, Denmark
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  • Foulum - Blichers Allé 20, 8830 Tjele, Denmark
  • Flakkebjerg - Forsøgsvej 1, 4200 Slagelse, Denmark
  • MBG's teaching labs - C.F. Møllers Allé 4, 8000 Aarhus C, Denmark

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