News

2013.08.09 | Research news

Small adrenal tumours cause high blood pressure

In collaboration with a Cambridge research group, Danish researchers from the research centre PUMPkin at Aarhus University have revealed why up to 10 percent of the population have high blood pressure.

Somatic mutations in ATP1A1 and CACNA1D in APAs. (a) Schematic of Na+/K+ ATPase subunit ?1 and Cav 1.3. Colored circles indicate the positions where somatic alterations or deletions have been described in APAs.

2013.08.07 | Research news

New publication: Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension

Focus on our new research results by BBC! The new results have revealed the cause of elevated blood pressure in a large group of patients. It turns out to be linked to mutations in ion pumps in the cell membrane (the Na+,K+-ATPase) and in two different ion channels in the small adenomes of the adrenal glands, which causes an increased secretion of…